Created in NYC in the early 2000s, the Penicillin Cocktail isn't just a drink—it's a bold statement. With a base of blended Scotch, a float of smoky Islay whisky, and a spicy ginger-honey-lemon combo, it's the cocktail equivalent of a leather jacket over a tailored suit. In Los Angeles, it's the go-to for whiskey lovers who want something classic, but edgy.
From Hollywood whiskey bars to Malibu firepit parties, the Penicillin Cocktail is LA's smoky signature.
Ingredients For The Penicillin Cocktail (One Serving)
- 2 oz Blended Scotch Whisky
- ¾ oz Fresh Lemon Juice
- ¾ oz Honey-Ginger Syrup
- ¼ oz Islay Single Malt Scotch (float)
- Garnish: Candied ginger or lemon wheel
- Glass: Rocks
- Ice: Large cube or regular
LA Local Tip: We make our honey-ginger syrup in-house using local farmers market honey and fresh-pressed ginger juice. Prefer something smoky but subtle? Party Shakers offers an LA spin with mescal float as an alternative to Islay Scotch. The Penicillin Cocktail.
How to Make the Penicillin – LA Prescription Edition
1. Shake Scotch, lemon juice, and syrup with ice.
Get that balance of citrus and spice. The Penicillin Cocktail
- Strain into a rocks glass over fresh ice.
Clean, cold, and classy. - Float the Islay Scotch over the top.
Use a bar spoon for a slow, dramatic pour. - Garnish with candied ginger or lemon wheel.
This is your finishing flair—Instagram-ready.
Why Penicillin Is on Fire in LA
It's warm, intriguing, and unforgettable. The Penicillin is perfect for:
- Cold nights in Laurel Canyon
- Whiskey tastings in Silver Lake
- Private dinners in Venice
- Fireside celebrations in Topanga
The Penicillin Cocktail pairs beautifully with barbecue, aged cheeses, or roasted nuts.
FAQs
Is this too smoky for first-timers?
Not at all. The Islay float adds aroma and depth, but the honey-ginger base is smooth and crowd-friendly. We adjust smoke levels to taste.
Can I make this without Scotch?
Technically yes—but then it's not a Penicillin. We can offer a bourbon or mezcal version if you want a twist.
Can it be batched?
Yes—except for the float. We prep the base in advance and add the Islay Scotch per glass for maximum aroma.
Book the Penicillin – LA's Smoky Sip That Heals the Night
Smoky, spicy, and endlessly stylish—the Penicillin is your answer to a predictable drink menu. Other drinks are also available.
✅ Available across Los Angeles: DTLA, Silver Lake, Santa Monica, Laurel Canyon
✅ Customizable with mezcal, bourbon, or ginger intensity
✅ Ideal for whiskey bars, moody events, or fall/winter celebrations
✅ Delivered by expert Party Shakers with a story in every pour
Book Party Shakers – Prescribe the Penicillin and Elevate the Experience